#for_researcher

Polypharmacy as a Risk Factor for Clinically Relevant Sarcopenia: Results From the Berlin Aging Study II

M. König, D. Spira, I. Demuth, et al.

J Gerontol A Biol Sci Med Sci. 2017;73(1):117-122

This study have shown an independent association between polypharmacy and clinically relevant sarcopenia, based on the ALM/BMI-cutoffs defined by the FNIH sarcopenia project.

 

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Computed tomography abbreviated assessment of sarcopenia following trauma: The CAAST measurement predicts 6-month mortality in older adult trauma patients

C.M. Leeper, E. Lin, M. Hoffman, et al.

J Trauma Acute Care Surg. 2016;80(5):805-11

Older adult trauma patients are at increased risk of poor outcome, both immediately after injury and beyond hospital discharge. Identifying patients early in the hospital stay who are at increased risk of death after discharge can be challenging.

Results suggest that sarcopenia is a strong predictor of 6-month postdischarge mortality for older adults. The CAAST measurement is an efficient and inexpensive measure that can allow clinicians to target older trauma patients at risk of poor outcome for early intervention and/or palliative care services.

 

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Sarcopenia Is Associated With Lower Skeletal Muscle Capillarization and Exercise Capacity in Older Adults

S.J. Prior, A.S. Ryan, J.B. Blumenthal, et al.

J Gerontol A Biol Sci Med Sci. 2016;71(8):1096-101

In this study was tested the hypothesis that skeletal muscle capillarization and exercise capacity (VO2max) are lower in sarcopenic than in nonsarcopenic older adults and that the degree of sarcopenia is related to lower skeletal muscle capillarization.

Results obtained suggest that low skeletal muscle capillarization is one factor that may contribute to sarcopenia and reduced exercise capacity in older adults by limiting diffusion of substrates, oxygen, hormones, and nutrients.

 

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Use of the frailty index in evaluating the prognosis of older people in Beijing: A cohort study with an 8-year follow-up

L. Ma, L. Zhang, Z. Tang, et al.

Arch Gerontol Geriatr. 2016 ;64:172-7

The present study aimed to evaluate the prevalence of frailty and determine if the frailty index, a comprehensive geriatric assessment, was associated with the prognosis of older people in a Chinese population.

Results obtained suggests that the frailty index increases with age, and may be a significant tool for evaluation of the prognosis of older people in China.

 

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Measurements of skeletal muscle mass and power are positively related to a Mediterranean dietary pattern in women

E. Kelaiditi, A. Jennings, C.J. Steves, et al.

Osteoporos Int. 2016;27(11):3251-3260

The loss of skeletal muscle mass, strength, and function with age are contributing risk factors for the onset of sarcopenia, frailty, osteoporosis, fractures, and mortality. For the first time in a northern European population, it has been observed a significant positive association between the Mediterranean diet score and FFM% (fat-free mass / weight × 100) and leg explosive power (LEP, watts/kg) in healthy women that are potentially clinically relevant, independent of the factors known to influence muscle outcomes. These findings emphasize the potential role for overall diet quality based on the Mediterranean diet in the prevention of age-related loss of skeletal muscle outcomes.

 

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The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient

W.M. Sipers, L.B. Verdijk, S.J. Sipers, et al.

J Am Med Dir Assoc. 2016;17(5):466

The loss of skeletal muscle mass, strength, and function with age are contributing risk factors for the onset of sarcopenia, frailty, osteoporosis, fractures, and mortality. For the first time in a northern European population, it has been observed a significant positive association between the Mediterranean diet score and FFM% (fat-free mass / weight × 100) and leg explosive power (LEP, watts/kg) in healthy women that are potentially clinically relevant, independent of the factors known to influence muscle outcomes. These findings emphasize the potential role for overall diet quality based on the Mediterranean diet in the prevention of age-related loss of skeletal muscle outcomes.

 

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Resveratrol enhances exercise-induced cellular and functional adaptations of skeletal muscle in older men and women

S.E. Alway, J.L. McCrory, K. Kearcher, et al.

J Gerontol A Biol Sci Med Sci. 2017;72(12):1595-1606

Data obtained indicate a novel anabolic role of resveratrol in exercise-induced adaptations of older persons and this suggests that resveratrol combined with exercise might provide a better approach for reversing sarcopenia than exercise alone.

 

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Prevalence of muscle weakness based on different diagnostic criteria in community-dwelling older adults: a comparison of grip strength dynamometers

M. Kim and S. Shinkai

Geriatr Gerontol Int. 2017;17(11)2089-2095

The present study compared the performance of the Jamar and Smedley dynamometers for the measurement of grip strength, and the two dynamometers were used to determine the prevalence rate of weakness in a large, community-dwelling, older adult population, based on different diagnostic criteria.

 

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Sex differences in the effect of fish-oil supplementation on the adaptive response to resistance exercise training in older people: a randomized controlled trial

M. Da Boit, R. Sibson, S. Sivasubramaniam, et al.

Am J Clin Nutr. 2017;105(1):151-158

Long-chain n-3 PUFA supplementation augments the increases in muscle function and quality in older women but not in older men after resistance exercise training.

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