#for_researcher

Physical frailty, sarcopenia, and the enablement of autonomy: philosophical issues in geriatric medicine

A. Blasimme

Aging Clin Exp Res Epub 2017 Feb 10

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In this paper, I show that what in political and moral philosophy has come to be known as “the capability approach” may indeed provide much needed conceptual clarification in the area of frailty research.

Finnish

Preventing mobility disability in Europe: a health economics perspective from the SPRINTT study

N. Sirven, T. Rapp, S. Coretti, et al.

Aging Clin Exp Res Epub 2017 Feb 10

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The “Sarcopenia and Physical fRailty IN older people: multicomponenT Treatment strategies” (SPRINTT) project will provide a unique opportunity to explore health economics issues associated with frailty.

Finnish

The need of operational paradigms for frailty in older persons: the SPRINTT project

M. Cesari, E. Marzetti, R. Calvani, et al.

Aging Clin Exp Res Epub 2017 Feb 10

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The lack of consensus around a single operational definition has limited the clinical implementation of frailty in clinical practice.

In this context, the recently funded “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) project (largely based on such a novel approach) may indeed fill an important gap in the field and provide key insights for counteracting the disabling cascade in the elderly.

Finnish

Possibilities of ICT-supported services in the clinical management of older adults

M. Vollenbroek-Hutten, S. Jansen-Kosterink, M. Tabak, et al.

Aging Clin Exp Res Epub 2017 Feb 10

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Aim of this article is to describe the possible field of application for ICTsupported services in the management of older adults, in particular those with functional impairment.

Finnish

Physical frailty and sarcopenia (PF&S): a point of view from the industry

S. Del Signore and R.Roubenff

Aging Clin Exp Res Epub 2017 Feb 10

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We agree with regulators that better characterization of subpopulations, not only in elderly patients, can improve the benefit risk ratio of medicines. At the same time, we believe it is in the public health interest to develop novel drugs indicated for specific geriatric conditions.

Finnish

Biomarkers for physical frailty and sarcopenia

R. Calvani, F. Marini, M. Cesari, et al.

Aging Clin Exp Res Epub 2017 Feb 10

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This review provides an overview of currently available biological markers for PF and sarcopenia, as well as a critical appraisal of strengths and weaknesses of traditional procedures for biomarker development in the field. A novel approach for biomarker identification and validation, based on multivariate methodologies, is also discussed.

 

Finnish

The “Sarcopenia and Physical fRailty IN older people: multicomponenT Treatment strategies” (SPRINTT) project: advancing the care of physically frail and sarcopenic older people

R. Bernabei, L. Mariotti, P. Bordes, et al.

Aging Clin Exp Res Epub 2017 Feb 10

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The absolute and relative number of people aged 65+ is on a sharp rise worldwide. Such a demographic transition is certainly a desirable result of the magnificent combination of socioeconomic development, technological, and medical advancements, and the establishment of solid public health systems.

Finnish

SPRINTT and the involvement of stakeholders: strategy and structure

R. Le Lain, C. Ignaszewski, I. Klingmann, et al.

Aging Clin Exp Res Epub 2017 Feb 10

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The present article describes the SPRINTT workpackage activities aimed at engaging the scientific discussion on the physical frailty and sarcopenia with the EMA as one of its interlocutor acknowledging the need to collaborate on this topic to foster a productive dialogue.

Finnish

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